AIM2 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-10974-20UL
60 ul
£183,00
E-AB-10974-60UL
120 ul
£272,00
E-AB-10974-120UL
200 ul
£420,00
E-AB-10974-200UL
Über dieses Produkt
- SKU:
- E-AB-10974
- Zusätzliche Namen:
- AIM 2;AIM2;Absent in melanoma 2;Aim2;Interferon-inducible protein AIM2;OTTHUMP00000035296;PYHIN4
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.8 mg/ml
- Weitere Details:
- Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-, AIM2 is thought to act as a tumor suppressor by repressing NFB transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human AIM2
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-aim2_polyclonal_antibody-e_ab_10974