ELP2 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-10941-20UL
60 ul
£183,00
E-AB-10941-60UL
120 ul
£272,00
E-AB-10941-120UL
200 ul
£420,00
E-AB-10941-200UL
Über dieses Produkt
- SKU:
- E-AB-10941
- Zusätzliche Namen:
- AU023723;ELP2;Elongation protein 2 homolog (S. cerevisiae);Elongator acetyltransferase complex subunit 2;Elongator complex protein 2;Epl2;FLJ10879;SHINC 2;SHINC-2;SHINC2;elongator protein 2;signal transducer and activator of transcription 3 interacti
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.4 mg/ml
- Weitere Details:
- One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ELP2
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-elp2_polyclonal_antibody-e_ab_10941