CDKN2AIP Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-10510-20UL
60 ul
£183,00
E-AB-10510-60UL
120 ul
£272,00
E-AB-10510-120UL
200 ul
£420,00
E-AB-10510-200UL
Über dieses Produkt
- SKU:
- E-AB-10510
- Zusätzliche Namen:
- CARF;CDKN2A interacting protein;CDKN2A-interacting protein;Calcium response factor;Cdkn2aip;Collaborator of ARF;FLJ20036;collaborates/cooperates with ARF (alternate reading frame) protein
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.3 mg/ml
- Weitere Details:
- CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CDKN2AIP
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-cdkn2aip_polyclonal_antibody-e_ab_10510