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Antikörper

AIFM1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-10123-20UL
60 ul
£183,00
E-AB-10123-60UL
120 ul
£272,00
E-AB-10123-120UL
200 ul
£420,00
E-AB-10123-200UL
Über dieses Produkt
SKU:
E-AB-10123
Zusätzliche Namen:
1;AIFM1;Apoptosis inducing factor;Apoptosis inducing factor 1;Apoptosis-inducing factor 1;CMTX4;COWCK;COXPD6;Harlequin;Hq;MGC111425;MGC5706;Neuropathy;axonal motor-s;mAIF;mitochondrial;mitochondrion associated
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.2 mg/ml
Weitere Details:
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
Host:
Rabbit
Immunogen:
Recombinant protein of human AIFM1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody