CASP4 Polyclonal Antibody
Produktgrößen
25 ul
£134,00
D-AB-10447L-25UL
100 ul
£291,00
D-AB-10447L-100UL
Über dieses Produkt
- SKU:
- D-AB-10447L
- Zusätzliche Namen:
- Apoptotic cysteine protease Mih1/TX;CASP-4;CASP4;Caspase 4 apoptosis related cysteine peptidase;Caspase-4 subunit 2;Caspase4;ICE(rel)-II;ICE(rel)II;ICEREL II;ICH2;Mih1/TX;Protease ICH-2;Protease TX;TX
- Anwendung:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the cysteine proteases that plays important roles in apoptosis,cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4,apoptosis-related cysteine peptidase",this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CASP4 protein expressed by E.coli
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-casp4_polyclonal_antibody-d_ab_10447l