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Antikörper

SDHB Polyclonal Antibody

Produktgrößen
25 ul
£134,00
D-AB-10362L-25UL
100 ul
£291,00
D-AB-10362L-100UL
Über dieses Produkt
SKU:
D-AB-10362L
Zusätzliche Namen:
Ip, DHSB, Iron sulfur subunit, Iron sulfur subunit of complex II, Iron-sulfur subunit of complex II, PGL 4, PGL4, SDH, SDH 1, SDH1, SDH2, SDHIP, SdhB, Succinate dehydrogenase [ubiquinone] iron sulfur protein mitocho, homolog of, mitochondrial,CWS2
Anwendung:
Immunohistochemistry
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Host:
Rabbit
Immunogen:
Recombinant Human SDHB protein expressed by E.coli
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody