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Antikörper

SNCA Polyclonal Antibody

Produktgrößen
25 ul
£134,00
D-AB-10173L-25UL
100 ul
£291,00
D-AB-10173L-100UL
Über dieses Produkt
SKU:
D-AB-10173L
Zusätzliche Namen:
PARK1,NACP,Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,SNCA
Anwendung:
Western Blot
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release.Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores.Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis.Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5.
Host:
Rabbit
Immunogen:
Recombinant Human SNCA protein expressed by E.coli
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody