HSPA5 Polyclonal Antibody
Produktgrößen
25 ul
£134,00
D-AB-10170L-25UL
100 ul
£291,00
D-AB-10170L-100UL
Über dieses Produkt
- SKU:
- D-AB-10170L
- Zusätzliche Namen:
- 78 kDa glucose-regulated protein,BIP,Binding-immunoglobulin protein,Endoplasmic reticulum chaperone BiP,GRP,GRP-78,GRP78,HEL-S-89n,HSP70 family protein,HSP70 family protein 5,HSPA,HSPA5,Heat shock protein family A member,Immunoglobulin heavy chai,MIF,MIF2
- Anwendung:
- Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen.Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate .Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR).In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to disrupt the dimerization of ERN1/IRE1, thereby inactivating ERN1/IRE1.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human HSPA5 protein expressed by E.coli
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hspa5_polyclonal_antibody-d_ab_10170l