AMPK alpha2 Polyclonal Antibody
Produktgrößen
25 ul
£134,00
D-AB-10161L-25UL
100 ul
£291,00
D-AB-10161L-100UL
Über dieses Produkt
- SKU:
- D-AB-10161L
- Zusätzliche Namen:
- 5'-AMP-activated protein kinase catalytic subunit alpha-2;AAPK2;ACACA kinase;AMPK alpha 2 chain;AMPK subunit alpha-2;AMPK2;AMPKa2;AMPKalpha2;Acetyl-CoA carboxylase kinase;HMGCR kinase;Hydroxymethylglutaryl-CoA reductase kinase;PRKAA;PRKAA2;Protein kinase
- Anwendung:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
- Host:
- Rabbit
- Immunogen:
- Recombinant Rat Ampk2 protein expressed by E.coli
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-ampk_alpha2_polyclonal_antibody-d_ab_10161l