Vcam1 Polyclonal Antibody
Produktgrößen
25 ul
£134,00
D-AB-10152L-25UL
100 ul
£291,00
D-AB-10152L-100UL
Über dieses Produkt
- SKU:
- D-AB-10152L
- Zusätzliche Namen:
- CD106,V-CAM 1,VCAM-1,Vascular cell adhesion protein 1,Vcam-1,Vcam1
- Anwendung:
- Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Rat Vcam1 protein expressed by Mammalian
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-vcam1_polyclonal_antibody-d_ab_10152l