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Antikörper

Recombinant Histone H3 (Mono Methyl Lys79) Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN302113L-50UL
100 ul
£402,00
AN302113L-100UL
Über dieses Produkt
SKU:
AN302113L
Zusätzliche Namen:
Histone H,H3C,H3/A,H3C2,H3C3,H3C4,H3C6,H3C7,H3C8,H3FA,H3C10,H3C11,H3C12,HIST1H3A,H3C1,Histone H3.1,Histone H3/a,Histone H3/b,H3FL,HIST1H3B,H3FC,HIST1H3C,H3FB,HIST1H3D,H3FD,HIST1H3E,H3FI,HIST1H3F,H3FH,HIST1H3G,H3FK,HIST1H3H,H3FF,HIST1H3I,H3FJ,HIST1H3J,H3/A,H3FA,H3FB,H3FC,H3FD,H3FF,H3FH,H3FI,H3FJ,H3FK,H3FL,Hist1h3a,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H3H,HIST1H3I,HIST1H3J,Histone H3.1,Histone H3/a,Histone H3/b,H3 histone family,H31,H3a,histone 1,Histone cluster 1,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l,member A
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A837
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
The E Epsilon-amino lysine acetylation of proteins is an important reversible modification controlling protein activity. The amino-terminal tails of core histones undergo lysine methylation in multiple sites, termed as "histone code" or "epigenetic code". Lysine methylation in core histones is a major determinant for the formation of active and inactive regions of the genome and therefore plays vital roles in multiple cellular events. In most species, lysine methylation occurs primarily on histones H3 (Lys4, 9, 27, 36, 79) and H4 (Lys20) and has been implicated in both transcriptional activation and silencing. Methylation in histones modulated by specific histone methyltransferases (HMTs)and histone demethylases (HDMs)is impaired in the pathologies of cancer and other diseases and therefore, enzymes regulating histone lysine methylation have become promising targets for anti-cancer drugs.
Host:
Rabbit
Immunogen:
Monomethylated human histone H3 (Lys79) peptide
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies
Western Blot with Histone H3 (Mono Methyl Lys79) Monoclonal Antibody at dilution of 1:2000. Lane 1: BRL, Lane 2: N2a
Immunohistochemistry of paraffin-embedded Human breast cancer using Histone H3 (Mono Methyl Lys79) Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Mouse stomach using Histone H3 (Mono Methyl Lys79) Monoclonal Antibody at dilution of 1:100.
Immunofluorescent analysis of (4% Paraformaldehyde) fixed Rat liver cells using anti-Histone H3 (Mono Methyl Lys79) Monoclonal Antibody at dilution of 1:100.