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Antikörper

Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN302108L-50UL
100 ul
£402,00
AN302108L-100UL
Über dieses Produkt
SKU:
AN302108L
Zusätzliche Namen:
Histone H,H3C,H3/A,H3C2,H3C3,H3C4,H3C6,H3C7,H3C8,H3FA,H3C10,H3C11,H3C12,HIST1H3A,H3C1,Histone H3.1,Histone H3/a,Histone H3/b,H3FL,HIST1H3B,H3FC,HIST1H3C,H3FB,HIST1H3D,H3FD,HIST1H3E,H3FI,HIST1H3F,H3FH,HIST1H3G,H3FK,HIST1H3H,H3FF,HIST1H3I,H3FJ,HIST1H3J,H3/A,H3FA,H3FB,H3FC,H3FD,H3FF,H3FH,H3FI,H3FJ,H3FK,H3FL,Hist1h3a,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H3H,HIST1H3I,HIST1H3J,Histone H3.1,Histone H3/a,Histone H3/b,H3 histone family,H31,H3a,histone 1,Histone cluster 1,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l,member A
Anwendung:
ChIP, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A832
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Histone post-translational modifications (PTMs) are key mechanisms of epigenetics that modulate chromatin structures, termed as "histone code". The PTMs on histone including acetylation, methylation, phosphorylation and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability, gene transcription, etc. Histone methylation occurs primarily at lysine and arginine residues on the amino terminal of core histones. Methylation of histones can either increase or decrease transcription of genes, depending on which amino acids (Lys or Arg) in the histones are methylated and how many methyl groups are attached (mono-, di-, Trimethylation on Lys, mono-di-symmetric/asymmetric methylation on Arg). Mostly, lysine methylation occurs primarily on histone H3 Lys4, 9, 27, 36, 79 and H4 Lys20, while Arginine methylation occurs primarily on histone H3 Arg2, 8, 17, 26 and H4 Arg3. histone methyltransferases (HMTs) and histone demethylases (HDMs) are major regulating factors.
Host:
Rabbit
Immunogen:
Dimethylated human histone H3 (Lys14) peptide
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies