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Antikörper

Recombinant Histone H3.3 Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN302024L-50UL
100 ul
£402,00
AN302024L-100UL
Über dieses Produkt
SKU:
AN302024L
Zusätzliche Namen:
H3F,histone H,H3F3A,H3.3A,H3F3,histone H3.3,family 3B (H3.3B),H3 histone,H3 histone family 3A,H3 histone family 3B,H3.3,H33,Histone H3.3Q,Histone H3.A,Histone H3.B,MGC87782,MGC87783,H3.3B,H3F3B,H3-3A,H3-3B,PP781
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A744
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Histone H3.3 is a histone H3 variant that replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Host:
Rabbit
Immunogen:
Peptide. This information is proprietary to PTMab.
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies