Recombinant CD39 Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301981L-50UL
100 ul
£402,00
AN301981L-100UL
Über dieses Produkt
- SKU:
- AN301981L
- Zusätzliche Namen:
- SPG,Ecto-ATP diphosphohydrolase,Ectonucleoside triphosphate diphosphohydrolase,ENTPD,ENTPD1,ATPDase,CD39,NTPDase-1,SPG64,CD 39,NTPDase1,Ecto-apyrase,Ectonucleoside triphosphate diphosphohydrolase 1,NTPDase 1,Ecto-ATP diphosphohydrolase 1,Lymphoid cell activation antigen,NTPDase-1,CD39 antigen,DKFZp686D194,DKFZp686I093,Ecto apyrase,Ecto ATP diphosphohydrolase,Ecto-ATPase 1,Ecto-ATPDase 1,ENTP1,ENTPD 1,FLJ40921,FLJ40959
- Anwendung:
- Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A701
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CD39,also known as ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1), is a multi-pass membrane ectoenzyme that metabolizes adenosine-5'-triphosphate (ATP) to regulate purinergic signaling. Purinergic signaling by extracellular ATP and its metabolites regulate many biological processes, including vascular tone, digestion, neuronal function, and inflammation in both normal and diseased states. CD39 is expressed in endothelial cells in the vasculature to regulate local platelet purinergic signaling via metabolism of ATP to adenosine. Accordingly, CD39 regulates platelet activation aggregation and contributes to the antithrombotic properties of endothelial cells. ATP and its metabolites also finely modulate the activity of T cells and macrophages. Immunomodulation is regulated, in part, by the availability of extracellular ATP and adenosine, suggesting that CD39 may play an immunosuppressive role in the tumor microenvironment.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_cd39_monoclonal_antibody-an301981l