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Antikörper

Recombinant COUP-TFII Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN301980L-50UL
100 ul
£402,00
AN301980L-100UL
Über dieses Produkt
SKU:
AN301980L
Zusätzliche Namen:
SVP,COT,CHTD,NF-E,COUP transcription factor,Apolipoprotein AI regulatory protein,Apolipoprotein A-I regulatory protein,Nuclear receptor subfamily 2 group F member,TFCOUP,COUP TF,COUP-TF,ARP,NR2F2,ARP1,CHTD4,COUPTFB,COUPTFII,NF-E3,SVP40,TFCOUP2,Apolipoprotein AI regulatory protein 1,Apolipoprotein A-I regulatory protein 1,ARP-1,COT2,COUP TF2,COUP transcription factor 2,COUP transcription factor II,COUP-TF II,COUP-TF2,NR2F1,Nuclear receptor subfamily 2 group F member 2
Anwendung:
ChIP, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A696
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) belongs to the NR2 subfamily of the nuclear hormone receptor family. COUP-TFI and COUP-TFII are two of the well-characterized members in the NR2 subfamily. These two members are highly conserved in their two zinc-finger DNA binding domains (DBD) and the ligand binding domain (LBD), and function as repressors or activators of downstream target genes to regulate different biological processes. COUP-TFI and II bind to 5'-AGGTCA-3' motif palindromes, either directly or indirectly, through heterodimer formation with other proteins (e.g. RXRs) to regulate downstream target gene expression. COUP-TFI is involved in neuronal development, tissue patterning, and differentiation. COUP-TFII has been shown to be involved in angiogenesis, glucose homeostasis, and mesenchymal cell commitment.
Host:
Rabbit
Immunogen:
Peptide. This information is proprietary to PTMab.
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies
Western Blot with COUP-TFII Monoclonal Antibody at dilution of 1:1000. Lane 1: MCF-7, Lane 2: K562, Lane 3: PC-12
Immunohistochemistry of paraffin-embedded Human breast cancer using COUP-TFII Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Mouse testis using COUP-TFII Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Rat testis using COUP-TFII Monoclonal Antibody at dilution of 1:100.
Chromatin immunoprecipitation analysis of MCF-7 immunoprecipitated DNA by real-time PCR using primers specific for the human TACSTD2-E, CYP24A1-E1, CYP24A1-E2, ZNF217-E1 and ZNF217-E2. The data are presented as enrichment of each sample relative to the total amount of input chromatin at each amplicon.