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Antikörper

Recombinant SOX17 Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN301960L-50UL
100 ul
£402,00
AN301960L-100UL
Über dieses Produkt
SKU:
AN301960L
Zusätzliche Namen:
VUR,SOX,VUR3,SOX17
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A676
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
SRY-related high mobility group box (SOX) proteins comprise a large family of widely conserved transcription factors. SOX proteins do not directly mediate transcription, but require binding partners that regulate their ability to mediate transcription of target genes that control cell fate determination and development .Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Sox17 negatively regulates oligodendrocyte precursor differentiation by antagonizing B Beta-catenin signaling. Mutation in the corresponding Sox17 gene in humans is associated with a form of vesicoureteral reflux, a disorder characterized by congenital kidney and urinary tract defects.
Host:
Rabbit
Immunogen:
Recombinant human SOX17 fragment
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies