Recombinant SGK1 Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301954L-50UL
100 ul
£402,00
AN301954L-100UL
Über dieses Produkt
- SKU:
- AN301954L
- Zusätzliche Namen:
- SGK1,SGK,OTTHUMP00000017247,Serine/threonine protein kinase SGK,Serine/threonine protein kinase Sgk1,Serine/threonine-protein kinase Sgk1,Serum and glucocorticoid regulated kinase,Serum/glucocorticoid regulated kinase,Serum/glucocorticoid regulated kinase 1,Serum/glucocorticoid-regulated kinase 1,SGK 1,Sgk1 variant i3
- Anwendung:
- Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A670
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways. Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation. SGK also plays an important role in activating certain potassium, sodium, and chloride channels, suggesting its involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. SGK is negatively regulated by ubiquitination and proteasome degradation.In addition to its membrane channel and carrier functions, SGK1 also regulates a broad range of targets, such as GSK-3, NEDD4, iNOS, AMPAR, PSD95, Tau, NF-K KappaB, CREB, and FKHR-L1.
- Host:
- Rabbit
- Immunogen:
- Recombinant human SGK1 fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_sgk1_monoclonal_antibody-an301954l