Recombinant RXRA Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301943L-50UL
100 ul
£402,00
AN301943L-100UL
Über dieses Produkt
- SKU:
- AN301943L
- Zusätzliche Namen:
- NR2B,NR2B1,RXRA,Retinoid X receptor alpha
- Anwendung:
- Immunofluorescence, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A659
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Retinoid X receptor A Alpha (RXRA) is the founding RXR family member and is predominantly expressed in the liver, kidney, epidermis, intestine, and a variety of tissues. Knockout of the murine rxrA Alpha gene results in embryonic lethality tentatively due to myocardial hypoplasia, which demonstrates the importance of RXRA in retinoid signaling in vivo. Biochemical evidence suggests that RXRA transcriptional activity is post-translationally regulated through the Ras-Raf-MAPK signaling cascade. MAPK-dependent phosphorylation of RXRA Alpha directly abrogates the ability of RXRA to associate with nuclear receptor coactivators.
- Host:
- Rabbit
- Immunogen:
- Recombinant human RXRA fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_rxra_monoclonal_antibody-an301943l