Recombinant CHD4 Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301933L-50UL
100 ul
£402,00
AN301933L-100UL
Über dieses Produkt
- SKU:
- AN301933L
- Zusätzliche Namen:
- CHD,CHD4,CHD-4,Mi-2b,Mi2-BETA,SIHIWES
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A649
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Chromodomain helicase DNA-binding protein 4 (CHD4) is an ATP dependent chromatin remodeler and a major subunit of the repressive NuRD complex. This complex plays key roles in transcriptional regulation and reorganization and maintenance of chromatin structure, as it targets pericentromeric heterochromatin and has recently been implicated in DNA damage repair, being rapidly recruited to DNA double strand breaks. CHD4 is a novel BRIT1 binding partner that regulates the HR repair process, which is a critical pathway of repairing DNA double strand breaks and plays an essential role in maintaining genomic integrity. The calculated molecular weight of CHD4 is 218 kDa, but modified CHD4 is about 250-280 kDa.
- Host:
- Rabbit
- Immunogen:
- Recombinant human CHD4 fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_chd4_monoclonal_antibody-an301933l