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Antikörper

Recombinant Rab8A Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN301923L-50UL
100 ul
£402,00
AN301923L-100UL
Über dieses Produkt
SKU:
AN301923L
Zusätzliche Namen:
RAB,RAB8A,MEL,RAB8,AA409338,Mel transforming oncogene,Mel transforming oncogene (derived from cell line NK14),Mel transforming oncogene (derived from cell line NK14) RAB8 homolog,Mel transforming oncogene (RAB8 homolog),MGC124948,Oncogene c mel,Oncogene c-mel,RAB8A member RAS oncogene family,Ras associated protein RAB8,Ras related protein Rab 8A,Ras-related protein Rab-8A
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A639
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
The Rab8 GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8 has two isoforms, RAB8A and RAB8B, that share 40% amino acid identity in the C-terminal variable region. RAB8 activity is regulated by specific guanine nucleotide exchange factors (GEFs), that mediate GTP loading, and GTPase activating proteins (GAPs) that convert them into the inactive GDP-bound form. RAB8 participates in recycling of the A Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors to the dendritic spine surface as well as in the intracellular transport of the metabotropic glutamate receptor type 1 in neuronal cells. Rab8 is activated at the base of the cilium by its guanine nucleotide exchanger Rabin8.
Host:
Rabbit
Immunogen:
Recombinant human Rab8A fragment
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Non-human Primate
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies