Recombinant Glypican-3 Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301865L-50UL
100 ul
£402,00
AN301865L-100UL
Über dieses Produkt
- SKU:
- AN301865L
- Zusätzliche Namen:
- MXR,GPC,UNQ,PRO,CDw,ADAM,Protein FOAP,Secreted glypican,Glypican proteoglycan,Sialic acid-binding Ig-like lectin,C20orf,OCI,GPC3,DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS,SGBS1,glypican-3,CDw329,Glypican 3,Glypican proteoglycan 3,Glypican-3 [Precursor],GTR2 2,Heparan sulphate proteoglycan,Intestinal protein OCI 5,Intestinal protein OCI-5,OCI 5,Protein FOAP-9,Secreted glypican-3,Sialic acid-binding Ig-like lectin 9,SIGLEC9,Siglec-9,ADAM33,C20orf153,UNQ873,PRO1891,OCI5
- Anwendung:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A577
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Glypican 3 belongs to Glypicans (GPCs), a family of glycosylphosphatidylinositol (GPI)-anchored heparan sulphate proteoglycans (HSPGs) that may play a role in the control of cell division and growth regulation. In mammals, there are six GPCs (GPC1 to GPC6), all of which have a similar core-protein size of approx. 60 kDa and the clustering of glycosaminoglycan attachment site near the C-terminus. They are tethered to the cell surface by GPI linkages, which can be cleaved by endogenous phospholipases, thus releasing the protein. Glypican 3 (GPC3) is highly expressed in many tissues during development and plays an important role in the regulation of embryonic growth. Loss-of-function mutations of GPC3 result in the Simpson-Golabi-Behmel overgrowth syndrome (SGBS), and Gpc-3 null mice display developmental overgrowth. In hepatocellular carcinoma (HCC), the overexpression of glypican 3 has been demonstrated to be a reliable diagnostic indicator.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Glypican-3 fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_glypican_3_monoclonal_antibody-an301865l