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Antikörper

Recombinant SF3B3 Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN301841L-50UL
100 ul
£402,00
AN301841L-100UL
Über dieses Produkt
SKU:
AN301841L
Zusätzliche Namen:
SAP,SF3B,KIAA,Splicing factor 3B subunit,Spliceosome-associated protein,Spliceosome-associated protein 130,Splicing factor 3B subunit 3,SF3B3,KIAA0017,SAP130,Pre mRNA splicing factor SF3b 130 kDa subunit,Pre-mRNA-splicing factor SF3b 130 kDa subunit,RSE1,SAP 130,SF3b130,SF3B3_HUMAN,Spliceosome associated protein 130,Splicing factor 3b subunit 3 130kD,STAF130
Anwendung:
Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A553
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
SF3B3 is one of four proteins for SF3B, which is involved in RNA splicing. Introns are removed from nuclear pre-mRNA in 2-step transesterification reactions. Splicing occurred in a large ribonucleoprotein particle, called the spliceosome. Spliceosomal intermediate complexes form on pre-mRNA in the order E, A, B, and C, with the catalytic reactions occurring in complex C. U2 small nuclear ribonucleoproteins are one of the proteins essential for spliceosome assembly and mRNA splicing. Functional U2 snRNP is composed of a 12S unit and 2 splicing factors, SF3A, which is composed of 3 proteins, and SF3B, which composed of 4 proteins. SF3B3 is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA.
Host:
Rabbit
Immunogen:
Recombinant human SF3B3 fragment
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies