Recombinant NF-kB2 p100/p52 Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301826L-50UL
100 ul
£402,00
AN301826L-100UL
Über dieses Produkt
- SKU:
- AN301826L
- Zusätzliche Namen:
- CVID,H2TF,NFKB,NF-kB,p49/p,LYT,CVID10,H2TF1,LYT-10,LYT10,NF-kB2,p100,p49/p100,p52,NFKB2,p105
- Anwendung:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A538
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. In a non-canonical activation pathway, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function.
- Host:
- Rabbit
- Immunogen:
- Recombinant human NF-kB2 p100/p52 fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p52_monoclonal_antibody-an301826l