Recombinant ATG9A Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301795L-50UL
100 ul
£402,00
AN301795L-100UL
Über dieses Produkt
- SKU:
- AN301795L
- Zusätzliche Namen:
- MGD,mATG,APG9L,ATG9A,APG9L1,MGD3208,mATG9,APG9 autophagy 9-like 1,APG9 like 1,APG9-like 1,ATG9,ATG9 autophagy related 9 homolog A,ATG9 autophagy related 9 homolog A (S. cerevisiae),Autophagy 9-like 1 protein,Autophagy related 9A,Autophagy related protein 9A,Autophagy-related protein 9A,OTTHUMP00000206046,OTTHUMP00000206048,OTTHUMP00000206049,OTTHUMP00000206062
- Anwendung:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A507
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- ATG9A are lipid scramblases that play a role in autophagosome expansion. ATG9A is present in numerous intracellular compartments, including the trans-Golgi network and early and recycling endosomes, and traffics through the secretory pathway to the plasma membrane and to the endocytic pathway from the plasma membrane. ATG9A protects cells against plasma membrane damage caused by a spectrum of exogenous and endogenous agents, including permeabilization by gasdermin and mixed lineage kinase domain like (MLKL), which generate pores at the plasma membrane or perturb plasma membrane integrity, respectively, during programmed cell death processes of pyroptosis and necroptosis. We furthermore define the ATG9A-IQGAP1 apparatus that integrates with the ESCRT system to cooperatively heal areas of plasma membrane damage.
- Host:
- Rabbit
- Immunogen:
- Recombinant human ATG9A fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_atg9a_monoclonal_antibody-an301795l