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Antikörper

Recombinant LSD2/AOF1 Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN301732L-50UL
100 ul
£402,00
AN301732L-100UL
Über dieses Produkt
SKU:
AN301732L
Zusätzliche Namen:
AOF,LSD,C6orf,AOF1,C6orf193,LSD2,KDM1B
Anwendung:
Flow Cytometry, Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A440
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
LSD2, also known as AOF1, is a Lysine (K)-specific demethylase that is encoded by the KDM1B gene in human. LSD2 demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD2 demethylates both mono- and Dimethylated 'Lys-4' of histone H3. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.
Host:
Rabbit
Immunogen:
Recombinant human LSD2/AOF1 fragment
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies
Western Blot with LSD2/AOF1 Monoclonal Antibody at dilution of 1:1000. Lane 1: SH-SY5Y
Western Blot with LSD2/AOF1 Monoclonal Antibody at dilution of 1:2000. Lane 1: K-562
Immunofluorescent analysis of (4% Paraformaldehyde) fixed HeLa cells using anti-LSD2/AOF1 Monoclonal Antibody at dilution of 1:50.
Flow cytometric analysis of human LSD2/AOF1 expression on HeLa cells. Cells were stained with purified anti-Human LSD2/AOF1, then a Alexa Fluor 488-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.