Recombinant HIP2/LIG Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301704L-50UL
100 ul
£402,00
AN301704L-100UL
Über dieses Produkt
- SKU:
- AN301704L
- Zusätzliche Namen:
- HIP,UBC,UBE2K,E2-25K,HIP2,HYPG,LIG,UBC1,HIP-2,Huntingtin-Interacting Protein 2,Ubiquitin Carrier Protein,Ubiquitin-Conjugating Enzyme E2 K,Ubiquitin-Conjugating Enzyme E2(25K),Ubiquitin-Conjugating Enzyme E2-25 kDa,Ubiquitin-Conjugating Enzyme E2-25K,Ubiquitin-Protein Ligase
- Anwendung:
- Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A412
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Huntingtin-interacting protein 2 (HIP2/LIG), is a E2 ubiquitin-conjugating enzyme, which accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, HIP2/LIG catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, while it does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Moreover, HIP2/LIG mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins.
- Host:
- Rabbit
- Immunogen:
- Recombinant human HIP2/LIG fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:lig_monoclonal_antibody-an301704l