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Antikörper

Recombinant MUC1 Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN301606L-50UL
100 ul
£402,00
AN301606L-100UL
Über dieses Produkt
SKU:
AN301606L
Zusätzliche Namen:
MAM,CA 15,MUC,ADMCKD,ADMCKD1,CA 15-3,CD227,EMA,H23AG,KL-6,MAM6,MCD,MCKD,MCKD1,MUC-1,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,MUC1,CA15-3,mucin-1,CA15 3,CA153,Episialin,Carcinoma associated mucin,MUC 1,MUC1 beta,MUC1 CT,MUC1 NT,Mucin 1,Peanut reactive urinary mucin,Polymorphic epithelial mucin,Tumor associated mucin,MUC1/CA15-3 C-terminal,EMA,mucin 1,Breast carcinoma-associated antigen DF3,Cancer antigen 15-3,Carcinoma-associated mucin,Krebs von den Lungen-6,Peanut-reactive urinary mucin,Tumor-associated epithelial membrane antigen,Tumor-associated mucin
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A309
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
Host:
Rabbit
Immunogen:
Recombinant human MUC1 fragment
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies