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Antikörper

Recombinant CD25 Monoclonal Antibody

Produktgrößen
50 ul
£281,00
AN301472L-50UL
100 ul
£402,00
AN301472L-100UL
Über dieses Produkt
SKU:
AN301472L
Zusätzliche Namen:
IMD,IDDM,IL2RA,CD25,IDDM10,IL2R,IMD41,TCGFR,p55,IL-2 receptor subunit alpha,IL-2R subunit alpha,IL2-RA,IL-2-RA,IL-2RA Alpha,Interleukin-2 receptor subunit alpha,TAC antigen,Tac,p55,IL-2R&amp,alpha,alpha chain,CD25 antigen,IL 2 receptor alpha subunit,IL2 RA,Interleukin 2 receptor,Interleukin 2 receptor alpha,Interleukin 2 receptor alpha chain,t-cell growth factor receptor
Anwendung:
Flow Cytometry, Immunofluorescence
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A167
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk.
Host:
Rabbit
Immunogen:
Recombinant human CD25 fragment
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies
Immunofluorescent analysis of (4% Paraformaldehyde) fixed Jurkat cells using anti-CD25 Monoclonal Antibody at dilution of 1:50.
Immunofluorescent analysis of (4% Paraformaldehyde) fixed K562 cells using anti-CD25 Monoclonal Antibody at dilution of 1:50.
Flow cytometric analysis of human CD25 expression on Jurkat cells. Cells were stained with purified anti-Human CD25, then a Alexa Fluor 488-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.