Recombinant BCL6 Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301444L-50UL
100 ul
£402,00
AN301444L-100UL
Über dieses Produkt
- SKU:
- AN301444L
- Zusätzliche Namen:
- ZNF,LAZ,ZBTB,BCL,BCL6,BCL5,BCL6A,LAZ3,ZBTB27,ZNF51
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A139
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation.
- Host:
- Rabbit
- Immunogen:
- Recombinant human BCL6 fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_bcl6_monoclonal_antibody-an301444l