Recombinant AKT1 Monoclonal Antibody
Produktgrößen
50 ul
£281,00
AN301428L-50UL
100 ul
£402,00
AN301428L-100UL
Über dieses Produkt
- SKU:
- AN301428L
- Zusätzliche Namen:
- CWS,MGC,AKT serine/threonine kinase,AKT,CWS6,PKB,PKB-ALPHA,PRKBA,RAC,RAC-ALPHA,AKT1,AKT 1,AKT serine/threonine kinase 1,AKT1_HUMAN,MGC99656,Protein kinase B,Protein Kinase B Alpha,Proto-oncogene c-Akt,RAC Alpha,RAC-alpha serine/threonine-protein kinase,RAC-PK-alpha,AKT,AKT serine/threonine kinase 1,CWS6,PKB,PKB-ALPHA,PRKBA,RAC,RAC-ALPHA
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A123
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
- Host:
- Rabbit
- Immunogen:
- Recombinant human AKT1 fragment
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_akt1_monoclonal_antibody-an301428l