Recombinant PMS2 Monoclonal Antibody
Produktgrößen
100 ul
£346,00
AN301379L-100UL
Über dieses Produkt
- SKU:
- AN301379L
- Zusätzliche Namen:
- MLH,PMS,PMSL,HNPCC,PMS2,HNPCC4,MLH4,PMS2CL,PMSL2
- Anwendung:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B1146
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human PMS2 protein
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_pms2_monoclonal_antibody-an301379l