Recombinant 53BP1 Monoclonal Antibody
Produktgrößen
100 ul
£346,00
AN301369L-100UL
Über dieses Produkt
- SKU:
- AN301369L
- Zusätzliche Namen:
- 53BP,TDRD,tumor protein p53 binding protein,p53BP,TP53BP,TP53BP1,53BP1,TDRD30,TP53,p202,p53BP1,tumor protein p53 binding protein 1,53BP1,p202,p53BP1,TDRD30,TP53,tumor protein p53 binding protein 1
- Anwendung:
- Cell-based/Functional Assay, ChIP, ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B1136
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human 53BP1 protein
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_53bp1_monoclonal_antibody-an301369l