Recombinant Phospho-PDPK1 (Ser241) Monoclonal Antibody
Produktgrößen
100 ul
£346,00
AN301308L-100UL
Über dieses Produkt
- SKU:
- AN301308L
- Zusätzliche Namen:
- PDK,PRO,3-phosphoinositide-dependent protein kinase,PDPK1,PDK1,PDPK2,PDPK2P,PRO0461,3-phosphoinositide-dependent protein kinase 1,3-phosphoinositide-dependent protein kinase 1,PDK1,PDPK2,PDPK2P,PRO0461,3 phosphoinositide dependent protein kinase 1,hPDK 1,hPDK1,MGC20087,MGC35290,OTTHUMP00000159109,OTTHUMP00000159110,OTTHUMP00000174525,PkB kinase,PkB kinase like gene 1,PkB like 1,Protein kinase
- Anwendung:
- ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B1071
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM:Phosphorylated on tyrosine and serine/threonine. Phosphorylation on Ser-241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser-241, leading to its own activation.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDK1 subfamily.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane.,subunit:Interacts with TUSC4.,tissue specificity:Appears to be expressed ubiquitously.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to residues around (Ser241) of Human Phospho-PDPK1
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_phospho_pdpk1_(ser241)_monoclonal_antibody-an301308l