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Antikörper

Recombinant GluR-2 Monoclonal Antibody

Produktgrößen
50 ul
£246,00
AN301279L-50UL
100 ul
£346,00
AN301279L-100UL
Über dieses Produkt
SKU:
AN301279L
Zusätzliche Namen:
GRIA,GLUR,GluA,HBGR,GluR-K,GRIA2,GLUR2,GLURB,GluA2,GluR-K2,HBGR2,AMPA 2,AMPA selective glutamate receptor 2,AMPA2,AMPA-selective glutamate receptor 2,GLUR 2,GLUR B,GluR K2,GluR-2,GluR-B,Glutamate receptor 2,Glutamate receptor ionotropic,Glutamate receptor ionotropic AMPA 2,GluR-2
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B1042
Klonalität:
Recombinant Monoclonal
Konzentration:
0.2 mg/ml
Weitere Details:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->,CGG, Q->,R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology.
Host:
Rabbit
Immunogen:
Recombinant Human GluR-2 protein
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies