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Antikörper

Recombinant N6-methyladenosine (m6A) Monoclonal Antibody

Produktgrößen
50 ul
£246,00
AN301128L-50UL
100 ul
£346,00
AN301128L-100UL
Über dieses Produkt
SKU:
AN301128L
Zusätzliche Namen:
N6-methyladenosine,m6A
Anwendung:
Dot Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B883
Klonalität:
Recombinant Monoclonal
Konzentration:
0.2 mg/ml
Weitere Details:
Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848, PMID: 24662220, PMID: 30429466)
Host:
Rabbit
Immunogen:
Recombinant N6-methyladenosine (m6A) protein
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Wide/Non-species Specific
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies