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Antikörper

Recombinant PRKACA Monoclonal Antibody

Produktgrößen
50 ul
£246,00
AN300927L-50UL
100 ul
£346,00
AN300927L-100UL
Über dieses Produkt
SKU:
AN300927L
Zusätzliche Namen:
PPNAD,PRKACA,PKACA,PPNAD4,cAMP dependent protein kinase alpha catalytic subunit,cAMP dependent protein kinase beta catalytic subunit,cAMP dependent protein kinase catalytic beta subunit isoform 4ab,cAMP dependent protein kinase catalytic subunit alpha,cAMP dependent protein kinase catalytic subunit beta,cAMP-dependent protein kinase catalytic subunit alpha,isoform 1,KAPCA,PKA C alpha,PKA C beta,PKA C-alpha,PKACB,PRKACAA,PRKACB,Protein kinase A catalytic subunit,Protein kinase A catalytic subunit alpha,Protein kinase A catalytic subunit beta,Protein kinase cAMP dependent catalytic alpha,Protein kinase cAMP dependent catalytic beta,protein kinase cAMP-activated catalytic subunit alpha,PKA
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B874
Klonalität:
Recombinant Monoclonal
Konzentration:
0.2 mg/ml
Weitere Details:
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing&apos,s syndrome.
Host:
Rabbit
Immunogen:
Recombinant Human PRKACA protein
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies