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Antikörper

Recombinant IL-10 Monoclonal Antibody

Produktgrößen
50 ul
£246,00
AN300799L-50UL
100 ul
£346,00
AN300799L-100UL
Über dieses Produkt
SKU:
AN300799L
Zusätzliche Namen:
Interleukin,RP11-262N,CSIF,GVHDS,IL-10,IL10A,TGIF,IL10,Cytokine synthesis inhibitory factor,Interleukin-10,MGC126450,MGC126451,RP11-262N9.1
Anwendung:
ELISA, Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B742
Klonalität:
Recombinant Monoclonal
Konzentration:
0.2 mg/ml
Weitere Details:
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Host:
Rabbit
Immunogen:
Recombinant Human IL-10 protein
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies