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Antikörper

Recombinant MDM2 Monoclonal Antibody

Produktgrößen
50 ul
£246,00
AN300707L-50UL
100 ul
£346,00
AN300707L-100UL
Über dieses Produkt
SKU:
AN300707L
Zusätzliche Namen:
hdm,MDM,MDM2,ACTFS,HDMX,hdm2,Double minute 2 protein,E3 ubiquitin-protein ligase Mdm2,Hdm 2,MDM 2,MDM2 oncogene E3 ubiquitin protein ligase,Mdm2 p53 E3 ubiquitin protein ligase homolog,Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa,MDM2BP,Mouse Double Minute 2,MTBP,Murine Double Minute Chromosome 2,Oncoprotein Mdm2,p53 Binding Protein Mdm2,p53-binding protein Mdm2,Ubiquitin protein ligase E3 Mdm2
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B646
Klonalität:
Recombinant Monoclonal
Konzentration:
0.2 mg/ml
Weitere Details:
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Host:
Rabbit
Immunogen:
Recombinant Human MDM2 protein
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies