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Antikörper

Recombinant XIAP Monoclonal Antibody

Produktgrößen
50 ul
£246,00
AN300702L-50UL
100 ul
£346,00
AN300702L-100UL
Über dieses Produkt
SKU:
AN300702L
Zusätzliche Namen:
ILP,XLP,API,BIRC,Inhibitor of apoptosis protein,Baculoviral IAP repeat-containing protein,IAP,XIAP,API3,BIRC4,IAP-3,ILP1,MIHA,XLP2,hIAP-3,hIAP3,X-linked inhibitor of apoptosis,Baculoviral IAP repeat-containing protein 4,E3 ubiquitin-protein ligase XIAP,IAP-like protein,Inhibitor of apoptosis protein 3,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein,IAP3
Anwendung:
ELISA, Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B641
Klonalität:
Recombinant Monoclonal
Konzentration:
0.2 mg/ml
Weitere Details:
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Host:
Rabbit
Immunogen:
Recombinant Human XIAP protein
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies