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Antikörper

Recombinant PDPK1 Monoclonal Antibody

Produktgrößen
50 ul
£246,00
AN300667L-50UL
100 ul
£346,00
AN300667L-100UL
Über dieses Produkt
SKU:
AN300667L
Zusätzliche Namen:
PDK,PRO,3-phosphoinositide-dependent protein kinase,PDPK1,PDK1,PDPK2,PDPK2P,PRO0461,3-phosphoinositide-dependent protein kinase 1,3-phosphoinositide-dependent protein kinase 1,PDK1,PDPK2,PDPK2P,PRO0461,3 phosphoinositide dependent protein kinase 1,hPDK 1,hPDK1,MGC20087,MGC35290,OTTHUMP00000159109,OTTHUMP00000159110,OTTHUMP00000174525,PkB kinase,PkB kinase like gene 1,PkB like 1,Protein kinase
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B606
Klonalität:
Recombinant Monoclonal
Konzentration:
0.2 mg/ml
Weitere Details:
ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM:Phosphorylated on tyrosine and serine/threonine. Phosphorylation on Ser-241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser-241, leading to its own activation.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDK1 subfamily.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane.,subunit:Interacts with TUSC4.,tissue specificity:Appears to be expressed ubiquitously.
Host:
Rabbit
Immunogen:
Recombinant Human PDPK1 protein
Isotyp:
IgG, kappa
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies