Recombinant Raf-1 Monoclonal Antibody
Produktgrößen
50 ul
£246,00
AN300664L-50UL
100 ul
£346,00
AN300664L-100UL
Über dieses Produkt
- SKU:
- AN300664L
- Zusätzliche Namen:
- CMD1NN,CRAF,NS5,Raf-1,c-Raf,RAF1,RAF,Proto-oncogene c-RAF (cRaf),RAF proto-oncogene serine/threonine-protein kinase
- Anwendung:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B603
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Raf-1 protein
- Isotyp:
- IgG, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:p-recombinant_raf_1_monoclonal_antibody-an300664l