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Antikörper

Recombinant SLAMF8 Monoclonal Antibody

Produktgrößen
100 ul
£402,00
AN300540P-100UL
Über dieses Produkt
SKU:
AN300540P
Zusätzliche Namen:
SLAM family member,SBBI,Slamf,B-lymphocyte activator macrophage expressed,CD353,SBBI42,SLAM family member 8,Blame,Slamf8,BLAME,SBBI42
Anwendung:
IHC-Paraffin
Buffer:
PBS
translate.label.attr.clone:
B470
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition. SLAM family of receptors is expressed by a wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors associate with SLAM-associated protein (SAP)-related molecules, a group of cytoplasmic adaptors composed almost exclusively of an SRC homology 2 domain. SLAM family receptors, in association with SAP family adaptors, have crucial roles during normal immune reactions in innate and adaptive immune cells. Mouse SLAM family member 8, also known as B-lymphocyte activator macrophage expressed, BCM-like membrane protein, SLAMF8 and BLAME, is a single-pass type I membrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain. SLAMF8/BLAME is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
Host:
Rabbit
Immunogen:
Recombinant Mouse SLAMF8 Protein
Isotyp:
IgG
Aufreinigung:
Protein A Purified
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody