Recombinant CXADR Monoclonal Antibody
Produktgrößen
100 ul
£402,00
AN300458P-100UL
Über dieses Produkt
- SKU:
- AN300458P
- Zusätzliche Namen:
- Coxsackievirus and adenovirus receptor homolog,CVB3 BP,MCVADR,Car,Cxadr
- Anwendung:
- IHC-Paraffin
- Buffer:
- PBS
- translate.label.attr.clone:
- B384
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR.
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse CXADR protein
- Isotyp:
- IgG
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:p-recombinant_cxadr_monoclonal_antibody-an300458p