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Antikörper

Recombinant Phospho-Chk1 (Ser296) Monoclonal Antibody

Produktgrößen
20 ul
£167,00
AN300388L-20UL
100 ul
£402,00
AN300388L-100UL
Über dieses Produkt
SKU:
AN300388L
Zusätzliche Namen:
CHK,CHEK,CHEK1,CHK1
Anwendung:
Western Blot
Buffer:
10 mM sodium HEPES, 150 mM NaCl, 100 ug/mL protein protectant, 50% glycerol, pH 7.5
translate.label.attr.clone:
B314
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to the residues around
Isotyp:
IgG
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody