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Antikörper

Recombinant ALDH4A1 Monoclonal Antibody

Produktgrößen
100 ul
£402,00
AN300262P-100UL
Über dieses Produkt
SKU:
AN300262P
Zusätzliche Namen:
ALDH,ALDH4A,ALDH4,P5CDH,ALDH4A1,AL4A1,Aldehyde dehydrogenase,aldehyde dehydrogenase 4,aldehyde dehydrogenase 4 family,Aldehyde dehydrogenase family 4 member A1,Delta 1 pyrroline 5 carboxylate dehydrogenase,Delta-1-pyrroline-5-carboxylate dehydrogenase,family 4,L-glutamate gamma-semialdehyde dehydrogenase,member 1,member A1,mitochondrial,mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase,P5C dehydrogenase,P5CD,P5CDhL,P5CDhS,Pyrroline-5-carboxylate dehydrogenase,RP11 128M10.1,subfamily A
Anwendung:
Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
B180
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
ALDH4A1 is a member of the aldehyde dehydrogenase family. Aldehyde dehydrogenase enzymes function in the metabolism of many molecules including certain fats (cholesterol and other fatty acids) and protein building blocks (amino acids). Additional aldehyde dehydrogenase enzymes detoxify external substances, such as alcohol and pollutants, and internal substances, such as toxins that are formed within cells. ALDH4A1 is expressed abundantly in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas. It is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2). HP-2 is characterized by the accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. The disorder may be causally related to neurologic manifestations, including seizures and mental retardation.
Host:
Rabbit
Immunogen:
Recombinant Human ALDH4A1 Protein
Isotyp:
IgG
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies
Immunoprecipitation analysis using 2 uL anti-ALDH4A1 Monoclonal Antibody and 60 ug of Immunomagnetic beads Protein G. Western blot was performed from the immunoprecipitate using ALDH4A1 Monoclonal Antibody at a dilution of 1:100. Lane A:0.5 mg HepG2 Whole Cell Lysate
Western Blot with ALDH4A1 Monoclonal Antibody at dilution of 1:500. Lane A: HepG2 Whole Cell Lysate, Lane B: K562 Whole Cell Lysate, Lane C: A549 Whole Cell Lysate, Lysates/proteins at 30 ug per lane.