Recombinant MSH6/GTBP Monoclonal Antibody
Produktgrößen
20 ul
£189,00
AN300176P-20UL
100 ul
£402,00
AN300176P-100UL
Über dieses Produkt
- SKU:
- AN300176P
- Zusätzliche Namen:
- MSH,mutS homolog,HNPCC,MSH6,GTBP,GTMBP,HNPCC5,HSAP,p160,mutS homolog 6,GTBP,GTMBP,HNPCC5,HSAP,mutS homolog 6,p160
- Anwendung:
- IHC-Paraffin, Immunocytochemistry, Immunofluorescence
- Buffer:
- PBS
- translate.label.attr.clone:
- A1290
- Klonalität:
- Recombinant Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to the center region of the Human MSH6 / GTBP
- Isotyp:
- IgG
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human, Mouse, Non-human Primate, Other Mammal, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:gtbp_monoclonal_antibody-an300176p