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Antikörper

Recombinant Phospho-IGF1R (Tyr1131)/Insulin Receptor B Beta (Tyr1146) Monoclonal Antibody

Produktgrößen
20 ul
£189,00
AN300051L-20UL
100 ul
£402,00
AN300051L-100UL
Über dieses Produkt
SKU:
AN300051L
Zusätzliche Namen:
JTK,IGF1R,CD221,IGFIR,IGFR,JTK13,CD221 antigen,IGF-1R,IGF-I R,IGF-I receptor,IGF-IR,insulin-like growth factor 1 receptor
Anwendung:
Western Blot
Buffer:
10 mM sodium HEPES, 150 mM NaCl, 100 ug/mL protein protectant, 50% glycerol, pH 7.5
translate.label.attr.clone:
A1161
Klonalität:
Recombinant Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
A synthetic phosphopeptide corresponding to residues around Tyr1131 of the Human Phospho-IGF1R or Tyr1146 of the Human Insulin Receptor B Beta
Isotyp:
IgG
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Recombinant Antibodies