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Antikörper

CTLA-4 Monoclonal Antibody

Produktgrößen
100 ul
£346,00
AN200208P-100UL
Über dieses Produkt
SKU:
AN200208P
Zusätzliche Namen:
GRD;ALPS;IDDM;Cytotoxic T-lymphocyte protein;Cytotoxic T-lymphocyte-associated antigen;Cytotoxic T-Lymphocyte-Associated Protein;CELIAC;CTLA4;ALPS5;CD;CD152;CELIAC3;CTLA-4;GRD4;GSE;IDDM12;Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;Cytotoxic T-Lymphocyte-Associated Protein 4
Anwendung:
Western Blot
Buffer:
0.2 um filtered solution in PBS
translate.label.attr.clone:
A1060
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Host:
Mouse
Immunogen:
Recombinant Human CTLA-4 Protein
Isotyp:
IgG1
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody