BCL2/Bcl-2 Monoclonal Antibody
Produktgrößen
100 ul
£346,00
AN200169P-100UL
Über dieses Produkt
- SKU:
- AN200169P
- Zusätzliche Namen:
- B-cell Lymphoma;PPP1R;BCL;Bcl-2;PPP1R50;BCL2;apoptosis regulator Bcl-2;B-cell Lymphoma 2;apoptosis regulator Bcl-2;Bcl-2;PPP1R50;Apoptosis regulator Bcl 2;Apoptosis regulator Bcl2;AW986256;B cell CLL/lymphoma 2;B cell leukemia/lymphoma 2;B-cell;C430015F12Rik;D630044D05Rik;D830018M01Rik;Leukemia/lymphoma;Oncogene B-cell leukemia 2;Protein phosphatase 1;regulatory subunit 50;Bcl2
- Anwendung:
- Immunoprecipitation, Western Blot
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- A1021
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Bcl-2 is a member of a family of proteins that regulates outer mitochondrial membrane permeability. Bcl-2 is an anti-apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Bcl-2 is present on the outer mitochondrial membrane and is also found on other membranes in some cell types. Natural Bcl-2 contains a carboxyl-terminal mitochondria targeting sequence. Recombinant Bcl-2, missing the mitochondrial targeting sequence, maintains its ability to neutralize pro-apoptotic Bcl-2 family members. Neutralization by Bcl-2 appears to be through binding the BH3 region of pro-apoptotic Bcl-2 family members. This activity does not require the mitochondrial targeting sequence.
- Host:
- Mouse
- Immunogen:
- Recombinant Human BCL2/Bcl-2 protein
- Isotyp:
- IgG1
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:bcl_2_monoclonal_antibody-an200169p