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Antikörper

JAM-A/F11R Monoclonal Antibody

Produktgrößen
100 ul
£346,00
AN200027P-100UL
Über dieses Produkt
SKU:
AN200027P
Zusätzliche Namen:
PAM,UNQ,PRO,Platelet Adhesion Molecule,Junctional Adhesion Molecule,F11R,CD321,JAM,JAM1,JAMA,JCAM,KAT,PAM-1,JAM-1,JAM-A,Junctional Adhesion Molecule 1,Junctional Adhesion Molecule A,Platelet Adhesion Molecule 1,Platelet F11 Receptor,UNQ264,PRO301,JAM,JAM-A,F11R,CD 321,CD321 antigen,ESTM33,F11 receptor,homolog of,JAM 1,JAM A,Jcam1,Junction adhesion molecule,Junction adhesion molecule 1,Ly106,mouse,PAM 1,PAM1
Anwendung:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Buffer:
PBS
translate.label.attr.clone:
A871
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 2' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Host:
Mouse
Immunogen:
Recombinant Human JAM-A / F11R / CD321 protein
Isotyp:
IgG1
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
Flow cytometric analysis of human JAM-A(CD321) expression on SKBR3 cells. Cells were stained with purified anti-Human JAM-A(CD321), then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.
Immunofluorescence analysis of Human JAM-A in A431 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Mouse anti-Human JAM-A Monoclonal Antibody (1:100) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated (left panel, captured by laser confocal scanning microscope) and Alexa Fluor®594-conjugated (right panel, captured by fluorescence microscope) Goat Anti-mouse IgG secondary antibody, countstained with DAPI for nuclear staining (blue). Positive staining was localized to plasma membrane.